发表文章
近几年代表性文章：
Zuo R#, Li X#, Hu J#, Wang W#, Lu B, Zhang H, Cheng X, Lu W, Qin J*, Liu P*, Lu Y*. Prediction of ovarian cancer prognosis using statistical radiomic features of ultrasound images. Physics in Medicine and Biology, 2024 May 10, PMID: 38729170
Liu Y#, Yi J#, Wu P, Zhang J, Li X, Li J, Zhou L, Liu Y, Xu H, Chen E, Zhang H, Liang M, Liu P*, Pan X*, Lu Y*. Wemics: A Single‐Base Resolution Methylation Quantification Method for Enhanced Prediction of Epigenetic Regulation. Advanced Science, 2024, p.2308884.
Yu M#, Yi J#, Qiu Q#, Yao D, Li J, Yang J, Mi C, Zhou Y, Lu B, Lu W, Ying K, Chen W, Chen E, Zhang H, Lu Z*, Lu Y*, Liu P*. Pan-cancer tRNA-derived fragment CAT1 coordinates RBPMS to stabilize NOTCH2 mRNA to promote tumorigenesis. Cell Reports, 2023, 42:113408.
Hu J, Cui Z, Zhang X, Zhang J, Ge Y, Zhang H, Lu Y*, Shen D*.Uncertainty-aware refinement framework for ovarian tumor segmentation in CECT volume. Med Phys, 2023, doi: 10.1002/mp.16795.
Guo T#, Chen GQ#, Li XF#, Wang M, Liu KM, Yang XY, Liu SC, Feng YL, Liu PY*, Lin H*, Xie AY*. Small extrachromosomal circular DNA harboring targeted tumor suppressor gene mutations supports intratumor heterogeneity in mouse liver cancer induced by multiplexed CRISPR/Cas9. Genome Med, 2023, 15(1):80.
Widlansky ME#*, Liu Y#, Tumusiime S#, Hofeld B, Khan N, Aljadah M, Wang J, Anger A, Qiu Q, Therani B, Liu P, Liang M*. Coronary plaque sampling reveals molecular insights into coronary artery disease. Circ Res, 2023, 133(6):532-534.
Yi J#, Wu M#, Zheng Z, Zhou Q, Li X, Lu Y, Liu P*. Integrated analysis of DNA methylome and transcriptome reveals SFRP1 and LIPG as potential drivers of ovarian cancer metastasis. J Gynecol Oncol, 2023, 34:e71.
Yang Y#, Liu H#, Liu Y#, Zhou L, Zheng X, Yue R, Mattson DL, Kidambi S, Liang M, Liu P*, Pan X*. E-value: A superior alternative to P-value and its adjustments in DNA methylation studies. Brief Bioinform, 2023, Jun 27:bbad241.
Liu Y#, Huang J#, Pandey R, Liu P, Therani B, Qiu Q, Rao S, Geurts AM, Cowley AW Jr, Greene AS, Liang M*. Robustness of single-cell RNA-seq for identifying differentially expressed genes. BMC Genomics, 2023, Jul 3;24(1):371.
Williams AC, Singh V, Liu P, Kriegel AJ. Liquid biopsies poorly mirror renal ischemia-reperfusion injury. Non-Coding RNA, 2023, 9(2):24.
Amanullah M#, Pan M#, Lu K, Pan X, Lu Y, Luo D*, Liu P*. Tumor-infiltrating immune cell landscapes in the lymph node metastasis of papillary thyroid cancer. Curr Oncol, 2023, 30 (3):2625-2641.
Cheng X, Md A, Liu W, Liu Y, Pan X, Zhang H, Xu H, Liu P*, Lu Y*. WMDS.net: a network control framework for identifying key players in transcriptome programs. Bioinformatics, 2023, btad071.
Liu W, Yu M, Cheng S, Zhou X, Li J, Lu Y, Liu P*, Ding S*. tRNA-Derived RNA Fragments Are Novel Biomarkers for Diagnosis, Prognosis, and Tumor Subtypes in Prostate Cancer. Curr Oncol, 2023, 30(1):981-999.
Qian X, Liu P, Lu Y*. The role of non-coding RNA in tumorigenesis, development, diagnosis and treatment (in Chinese). Sci Sin Vitae, 2022, 52. doi:10.1360/SSV-2022-0087
Luo A#, Lan X#, Qiu Q#, Zhou Q, Li J, Wu M, Liu P, Zhang H, Lu B*, Lu Y*, Lu W*. LncRNA SFTA1P promotes cervical cancer progression by interaction with PTBP1 to facilitate TPM4 mRNA degradation. Cell Death & Disease, 2022, 13(11): 1-13
Yang J#, Qian X#, Qiu Q#, Xu L, Pan M, Li J, Ren J, Lu B, Qiu T, Chen E, Ying K, Zhang H, Lu Y*, Liu P*. LCAT1 is an oncogenic LncRNA by stabilizing the IGF2BP2-CDC6 axis. Cell Death Dis, 2022, 13:877.
Liu Z, Zhao C*, Lu Y, Jiang Y, Yan J. Multi-scale Graph Learning for Ovarian Tumor Segmentation from CT Images. Neurocomputing, 2022, 512:398-407.
Hu J#, Wang Z#, Zuo R#, Zheng C, Lu B, Cheng X, Lu W, Zhao C, Liu P*, Lu Y*. Development of survival predictors for high-grade serous ovarian cancer based on stable radiomic features from computed tomography images. iScience. 2022, 25:104628.
Wu M#, Qiu Q#, Zhou Q#, Li J, Yang J, Zheng C, Luo A, Li X, Zhang H, Cheng X, Lu W, Liu P*, Lu B*, Lu Y*. circFBXO7/miR-96-5p/MTSS1 axis is an important regulator in the Wnt signaling pathway in ovarian cancer. Mol Cancer. 2022, 21(1):137. doi: 10.1186/s12943-022-01611-y. PMID: 35768865
Zhou L#, Qiu Q#, Zhou Q#, Li J, Yu M, Li K, Xu L, Ke X, Xu H, Lu B, Wang H, Lu W*, Liu P*, Lu Y*. Long-read sequencing unveils high-resolution HPV integration and its oncogenic progression in cervical cancer. Nat Commun, 2022, 13(1):1-18. doi:10.1038/s41467-022-30190-1. PMID: 35538075
Chen F, Sun C, Yue Z, Zhang Y, Xu W, Shabbir S, Zou L, Lu W, Wang W, Xie Z, Zhou L, Lu Y*, Yu J*. Screening ovarian cancers with Raman spectroscopy of blood plasma coupled with machine learning data processing. Spectrochim Acta A Mol Biomol Spectrosc, 2021, 265:120355. doi: 10.1016/j.saa.2021.120355. PMID: 34530200
Qin J, Zhang S, Poon L, Pan Z, Luo J, Yu N, Wang L, Wu X, Cheng X, Xie X, Lu Y*, Lu W*. Doppler-based predictive model for methotrexate resistance in low-risk gestational trophoblastic neoplasia with myometrial invasion: prospective study of 147 patients. Ultrasound Obstet Gynecol, 2021, 57(5):829-839. doi: 10.1002/uog.22069. PMID: 32385928
Qian X#, Yang J#, Qiu Q#, Li X, Jiang C, Li J, Dong L, Ying K, Lu B, Chen E, Liu P*, Lu Y*. LCAT3, a novel m6A-regulated long non-coding RNA, plays an oncogenic role in lung cancer via binding with FUBP1 to activate c-MYC. J Hematol Oncol, 2021, 14(1):112.
Yue Z, Sun C, Chen F, Zhang Y, Xu W, Shabbir S, Zou L, Lu W, Wang W, Xie Z, Zhou L, Lu Y*, Yu J*. Machine learning-based LIBS spectrum analysis of human blood plasma allows ovarian cancer diagnosis. Biomedical Optics Express, 2021, 12(5):2559-2574, doi： 10.1364/BOE.421961
Qiu Q#, Zhou Q#, Luo A#, Li X, Li K, Li W, Yu M, Amanullah M, Lu B, Lu W*, Liu P*, Lu Y*. Integrated analysis of virus and host transcriptomes in cervical cancer in Asian and Western populations. Genomics, 2021, 113(3):1554-1564. doi: 10.1016/j.ygeno.2021.03.029.
Zhou L#, Wang W#, Wang F#, Yang S, Hu J, Lu B, Pan Z, Ma Y, Zheng M, Zhou L, Lei S, Song P, Liu P*, Lu W*, Lu Y*. Plasma-derived exosomal miR-15a-5p as a promising diagnostic biomarker for early detection of endometrial carcinoma. Mol Cancer, 2021, 20(1):57. doi: 10.1186/s12943-021-01352-4.
Sun X#, Yi J#, Yang J#, Han Y, Qian X, Liu Y, Li J, Lu B, Zhang J, Pan X, Liu Y, Liang M, Chen E*, Liu P*, Lu Y*. An integrated epigenomic–transcriptomic landscape of lung cancer reveals novel methylation driver genes of diagnostic and therapeutic relevance. Theranostics, 2021;11(11): 5346-5364. doi: 10.7150/thno.58385
Pan X#, Geng X#, Liu Y, Yu M, Mishra MK, Xu X, Ding X, Liu P*, Liang M*. Transfer RNA Fragments in the Kidney in Hypertension. Hypertension, 2021, 77(5):1627-1637. doi: 10.1161/HYPERTENSIONAHA.121.16994.
Zhang Y, Liu L, Qiu Q, Ding J*, Lu Y*, Liu P*. Alternative polyadenylation: methods, mechanism, function, and role in cancer. Journal of Experimental & Clinical Cancer Research, 2021, 40(1):51. doi: 10.1186/s13046-021-01852-7.
Sun X#, Yang J#, Yu M#, Yao D, Zhou L, Li X, Qiu Q, Lin W, Lu B, Chen E, Wang P, Chen W, Tao S, Xu H, Williams A, Liu Y, Pan X, Cowley A, Jr, Lu W, Liang M, Liu P*, Lu Y*. Global identification and characterization of tRNA-derived RNA fragment landscapes across human cancers. NAR Cancer, 2020, 2(4): zcaa031.
Yu M, Lu B, Zhang J, Ding J, Liu P, Lu Y*. tRNA-derived RNA fragments in cancer: current status and future perspectives. J Hematol Oncol 13, 121 (2020). https://doi.org/10.1186/s13045-020-00955-6
Liu Y, Han Y, Zhou L, Pan X, Sun X, Liu Y, Liang M, Qin J*, Lu Y*, Liu P*. A comprehensive evaluation of computational tools to identify differential methylation regions using RRBS data. Genomics. 2020;112(6):4567-4576. doi:10.1016/j.ygeno.2020.07.032
Yao D, Sun X, Zhou L, Amanullah M, Pan X, Liu Y, Liang M, Liu P*, Lu Y*. OncotRF: an online resource for exploration of tRNA-derived fragments in human cancers. RNA Biol. 2020;17(8):1081-1091. doi:10.1080/15476286.2020.1776506.
Han Y#,Liu Y#, Zhou L#, Chen E, Liu P, Pan X*, Lu Y*. Epidemiological Assessment of Imported Coronavirus Disease 2019 (COVID-19) Cases in the Most Affected City Outside of Hubei Province, Wenzhou, China. JAMA Netw Open. 2020;3(4):e206785. Published 2020 Apr 1. doi:10.1001/jamanetworkopen.2020.6785.
Amanullah M#, Yu M#, Sun X#, Luo A, Zhou Q, Zhou L, Hou L, Wang W, Lu W, Liu P*, Lu Y*. MDEHT: a Multivariate Approach for Detecting Differential Expression of MicroRNA Isoform Data in RNA Sequencing Studies Bioinformatics. 2020 May 1;36(9):2657-2664. doi: 10.1093/bioinformatics/btaa015.
Zheng Z, Chen E, Lu W, Mouradian G, Hodges M, Liang M, Liu P*, Lu Y*. Single cell transcriptomic analysis. Compr Physiol. 2020 Mar 12;10(2):767-783. doi: 10.1002/cphy.c190037.
Liu HY#, Zhou L#, Zheng MY#, Huang J, Wan S, Zhu A, Zhang M, Dong A, Hou L, Xu H, Lu B, Lu W, Liu P*, Lu Y*. Diagnostic and clinical utility of whole genome sequencing in a cohort of undiagnosed Chinese families with rare diseases. Sci Rep 9, 19365 (2019) doi:10.1038/s41598-019-55832-1.
Yang J#, Qiu Q#, Qian X, Yi J, Jiao Y, Yu M, Li X, Li J, Mi C, Zhang J, Lu B, Chen E, Liu P*, Lu Y*. Long noncoding RNA LCAT1 functions as a ceRNA to regulate RAC1 function by sponging miR-4715-5p in lung cancer. Mol Cancer. 2019;18(1):171. Published 2019 Nov 29. doi:10.1186/s12943-019-1107-y
Zhang L#, Zhou Q#, Qiu Q#, Hou L, Wu M, Li J, Li X, Lu B, Cheng X, Liu P, Lu W, Lu Y*. CircPLEKHM3 acts as a tumor suppressor through regulation of the miR-9/BRCA1/DNAJB6/KLF4/AKT1 axis in ovarian cancer. Mol Cancer. 2019;18(1):144. Published 2019 Oct 17. doi:10.1186/s12943-019-1080-5
Zheng M#, Hou L#, Ma Y#, Zhou L, Wang F, Cheng B, Wang W, Lu B, Liu P, Lu W, Lu Y*. Exosomal let-7d-3p and miR-30d-5p as diagnostic biomarkers for non-invasive screening of cervical cancer and its precursors. Mol Cancer. 2019;18(1):76. Published 2019 Apr 2. doi:10.1186/s12943-019-0999-x
Han Y#, Yang J#, Qian X, Cheng W, Liu S, Hua X, Zhou L, Yang Y, Wu Q, Liu P*, Lu Y*. DriverML: a machine learning algorithm for identifying driver genes in cancer sequencing studies. Nucleic acids research, doi:10.1093/nar/gkz096 (2019)
Lu B*, Teng X, Fu G, Bao L, Tang J, Sh H, Lu W, Lu Y*. Analysis of PD-L1 expression in trophoblastic tissues and tumors. Human pathology, 2019, 84: 202-212.
Sun X#, Han Y#, Zhou L, Chen E, Lu B, Liu Y, Pan X, Cowley AW Jr, Liang M, Wu Q, Lu Y*, Liu P*. A comprehensive evaluation of alignment software for reduced representation bisulfite sequencing data. Bioinformatics, 2018, 1: 9.
Yao D#, Zhang L#, Zheng M, Sun X, Lu Y*, Liu P*. Circ2Disease: a manually curated database of experimentally validated circRNAs in human disease. Scientific reports, 2018, 8(1): 11018.
Li X#, Li J#, Wu P, Zhou L, Lu B, Ying K, Chen E*, Lu Y*, Liu P*. Smoker and non-smoker lung adenocarcinoma is characterized by distinct tumor immune microenvironments. Oncoimmunology, 2018, 7(10): e1494677.
Liu P*, Liu Y, Liu H, Pan X, Li Y, Usa K, M Mishra, Nie J, Liang M*. Role of DNA De Novo (De)Methylation in the Kidney in Salt-Induced Hypertension. Hypertension, 2018, 72(5): 1160-1171.
Zhang H#, Lu Y#, Chen E#, Li X, Lv B, Vikis HG, Liu P*. XRN2 promotes EMT and metastasis through regulating maturation of miR-10a. Oncogene. 2017;36(27):3925-3933.
Liu P, Iden M, Fye S, Huang YW, Hopp E, Chu C, Lu Y, Rader JS. Targeted. Deep Sequencing Reveals Full Methylation Profiles of Multiple HPV Types and Potential Biomarkers for Cervical Cancer Progression. Cancer Epidemiol Biomarkers Prev. 2017;26(4):642-650.
Chu C, Fang Z, Hua X, Yang Y, Chen E, Cowley AW Jr, Liang M, Liu P*, Lu Y*. deGPS is a powerful tool for detecting differential expression in RNA-sequencing studies. BMC Genomics. 2015;16(1):455.
Li L, Chen E, Yang C, Zhu J, Jayaraman P, De Pons J, Kaczorowski CC, Jacob HJ, Greene AS, Hodges MR, Cowley AW Jr, Liang M, Xu H, Liu P*, Lu Y*. Improved rat genome gene prediction by integration of ESTs with RNA-Seq information. Bioinformatics. 2015;31(1):25-32.
Morrison CD#, Liu P#, Woloszynska-Read A, Zhang J, Luo W, Qin M, Bshara W, Conroy JM, Sabatini L, Vedell P, Xiong D, Liu S, Wang J, Shen H, Li Y, Omilian AR, Hill A, Head K, Guru K, Kunnev D, Leach R, Eng KH, Darlak C, Hoeflich C, Veeranki S, Glenn S, You M, Pruitt SC, Johnson CS, Trump DL. Whole Genome Sequencing Identifies Genomic Heterogeneity at a Nucleotide and Chromosomal Level in Bladder Cancer. Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):E672-81.
Kelly LM#, Barila G#, Liu P#, Evdokimova VN, Trivedi S, Panebianco F, Gandhi M, Carty SE, Hodak SP, Luo J, Dacic S, Yu YP, Nikiforova MN, Ferris RL, Altschuler DL, Nikiforov YE. Identification of the transforming STRN-ALK fusion as a potential therapeutic target in the aggressive forms of thyroid cancer. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4233-8.
Wang F, Li L, Xu H, Liu Y, Yang C, Cowley AW Jr, Wang N*, Liu P*, Liang M*. Characteristics of long non-coding RNAs in the Brown Norway rat and alterations in the Dahl salt-sensitive rat. Sci Rep. 2014 Nov 21;4:7146.
Liu Y#, Liu P#, Yang C, Cowley AW Jr, Liang M. Base-Resolution Maps of 5-Methylcytosine and 5-Hydroxymethylcytosine in Dahl S Rats: Effect of Salt and Genomic Sequence. Hypertension. 2014;63(4):827-38.
Hua X, Xu H, Yang Y, Zhu J, Liu P*, Lu Y*. DrGaP: A Powerful Tool for Identifying Driver Genes and Pathways in Cancer Sequencing Studies. Am J Hum Genet. 2013 Sep 5;93(3):439-51.
Lu Y, Liu P, Van den Bergh F, Zellmer V, James M, Wen W, Grubbs CJ, Lubet RA, You M. Modulation of gene expression and cell-cycle signaling pathways by the EGFR inhibitor gefitinib (Iressa) in rat urinary bladder cancer. Cancer Prev Res (Phila). 2012 Feb;5(2):248-59.
Lu Y, Govindan R, Wang L, Liu PY, Goodgame B, Wen W, Sezhiyan A, Pfeifer J, Li YF, Hua X, Wang Y, Yang P, You M. MicroRNA profiling and prediction of recurrence/relapse-free survival in stage I lung cancer. Carcinogenesis. 2012 May;33(5):1046-54.
Freedman ML, Monteiro AN, Gayther SA, Coetzee GA, Risch A, Plass C, Casey G, De Biasi M, Carlson C, Duggan D, James M, Liu P, Tichelaar JW, Vikis HG, You M, Mills IG. Principles for the post-GWAS functional characterization of cancer risk loci. Nat Genet. 2011 Jun;43(6):513-8.
Liu P, Morrison C, Wang L, Xiong D, Vedell P, Cui P, Hua X, Ding F, Lu Y, et al. Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing. Carcinogenesis. 2012;33(7):1270-6
Lu Y, Liu P, James M, Vikis HG, Liu H, Wen W, Franklin A, You M. Genetic variants cis-regulating Xrn2 expression contribute to the risk of spontaneous lung tumor. Oncogene. 2010 Feb 18;29(7):1041-9.
Liu P, Vikis H, James M, Lu Y, Wang DL, Liu HB, et al. Identification of Las2, a major modifier gene affecting the Pas1 mouse lung tumor susceptibility locus. Cancer Res. 2009;69:6290-8.
You M#*, Wang D#, Liu P#, Vikis H#, James M,Lu Y, et al. Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene. Clin Cancer Res. 2009;15:2666-74.
Liu P#, Yang P#, Wu X#, Vikis HG, Lu Y, Wang Y, et al. A second genetic variant on chromosome 15q24-25.1 associates with lung cancer. Cancer Res. 2010;70:3128-35.
Liu P, Vikis HG, Wang D, Lu Y, Wang Y, Schwartz AG, Pinney SM, Yang P, de Andrade M, Petersen GM, Wiest JS, Fain PR, Gazdar A, Gaba C, Rothschild H, Mandal D, Coons T, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Wu X, Spitz MR, Eisen T, Houlston RS, Amos CI, Anderson MW, You M. Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer. J Natl Cancer Inst. 2008 Sep 17;100(18):1326-30.
Lu Y, Lemon W, Liu PY, Yi Y, Morrison C, Yang P, Sun Z, Szoke J, Gerald WL, Watson M, Govindan R, You M. A gene expression signature predicts survival of patients with stage I non-small cell lung cancer. PLoS Med. 2006 Dec;3(12):e467.
Lu Y, Yao R, Yan Y, Wang Y, Hara Y, Lubet RA, You M. A gene expression signature that can predict green tea exposure and chemopreventive efficacy of lung cancer in mice. Cancer Res. 2006 Feb 15;66(4):1956-63.
Liu P, Wang Y, Vikis H, Maciag A, Wang D, Lu Y, Liu Y, You M. Candidate lung tumor susceptibility genes identified through whole-genome association analyses in inbred mice. Nat Genet. 2006 Aug;38(8):888-95.
Note: #, co-first author; *, co-corresponding author.
其它论文：
2023年文章
Yu M#, Yi J#, Qiu Q#, Yao D, Li J, Yang J, Mi C, Zhou Y, Lu B, Lu W, Ying K, Chen W, Chen E, Zhang H, Lu Z*, Lu Y*, Liu P*. Pan-cancer tRNA-derived fragment CAT1 coordinates RBPMS to stabilize NOTCH2 mRNA to promote tumorigenesis. Cell Reports, 2023, 42:113408.
Hu J, Cui Z, Zhang X, Zhang J, Ge Y, Zhang H, Lu Y*, Shen D*.Uncertainty-aware refinement framework for ovarian tumor segmentation in CECT volume. Med Phys, 2023, doi: 10.1002/mp.16795.
Guo T#, Chen GQ#, Li XF#, Wang M, Liu KM, Yang XY, Liu SC, Feng YL, Liu PY*, Lin H*, Xie AY*. Small extrachromosomal circular DNA harboring targeted tumor suppressor gene mutations supports intratumor heterogeneity in mouse liver cancer induced by multiplexed CRISPR/Cas9. Genome Med, 2023, 15(1):80.
Widlansky ME#*, Liu Y#, Tumusiime S#, Hofeld B, Khan N, Aljadah M, Wang J, Anger A, Qiu Q, Therani B, Liu P, Liang M*. Coronary plaque sampling reveals molecular insights into coronary artery disease. Circ Res, 2023, 133(6):532-534.
Yi J#, Wu M#, Zheng Z, Zhou Q, Li X, Lu Y, Liu P*. Integrated analysis of DNA methylome and transcriptome reveals SFRP1 and LIPG as potential drivers of ovarian cancer metastasis. J Gynecol Oncol, 2023, 34:e71.
Yang Y#, Liu H#, Liu Y#, Zhou L, Zheng X, Yue R, Mattson DL, Kidambi S, Liang M, Liu P*, Pan X*. E-value: A superior alternative to P-value and its adjustments in DNA methylation studies. Brief Bioinform, 2023, Jun 27:bbad241.
Liu Y#, Huang J#, Pandey R, Liu P, Therani B, Qiu Q, Rao S, Geurts AM, Cowley AW Jr, Greene AS, Liang M*. Robustness of single-cell RNA-seq for identifying differentially expressed genes. BMC Genomics, 2023, Jul 3;24(1):371.
Williams AC, Singh V, Liu P, Kriegel AJ. Liquid biopsies poorly mirror renal ischemia-reperfusion injury. Non-Coding RNA, 2023, 9(2):24.
Amanullah M#, Pan M#, Lu K, Pan X, Lu Y, Luo D*, Liu P*. Tumor-infiltrating immune cell landscapes in the lymph node metastasis of papillary thyroid cancer. Curr Oncol, 2023, 30 (3):2625-2641.
Cheng X, Md A, Liu W, Liu Y, Pan X, Zhang H, Xu H, Liu P*, Lu Y*. WMDS.net: a network control framework for identifying key players in transcriptome programs. Bioinformatics, 2023, btad071.
Liu W, Yu M, Cheng S, Zhou X, Li J, Lu Y, Liu P*, Ding S*. tRNA-Derived RNA Fragments Are Novel Biomarkers for Diagnosis, Prognosis, and Tumor Subtypes in Prostate Cancer. Curr Oncol, 2023, 30(1):981-999.
2022年文章
Qian X, Liu P, Lu Y*. The role of non-coding RNA in tumorigenesis, development, diagnosis and treatment (in Chinese). Sci Sin Vitae, 2022, 52. doi:10.1360/SSV-2022-0087
Luo A#, Lan X#, Qiu Q#, Zhou Q, Li J, Wu M, Liu P, Zhang H, Lu B*, Lu Y*, Lu W*. LncRNA SFTA1P promotes cervical cancer progression by interaction with PTBP1 to facilitate TPM4 mRNA degradation. Cell Death & Disease, 2022, 13(11): 1-13
Yang J#, Qian X#, Qiu Q#, Xu L, Pan M, Li J, Ren J, Lu B, Qiu T, Chen E, Ying K, Zhang H, Lu Y*, Liu P*. LCAT1 is an oncogenic LncRNA by stabilizing the IGF2BP2-CDC6 axis. Cell Death Dis, 2022, 13:877.
Liu Z, Zhao C*, Lu Y, Jiang Y, Yan J. Multi-scale Graph Learning for Ovarian Tumor Segmentation from CT Images. Neurocomputing, 2022, 512:398-407.
Hu J#, Wang Z#, Zuo R#, Zheng C, Lu B, Cheng X, Lu W, Zhao C, Liu P*, Lu Y*. Development of survival predictors for high-grade serous ovarian cancer based on stable radiomic features from computed tomography images. iScience. 2022, 25:104628.
Wu M#, Qiu Q#, Zhou Q#, Li J, Yang J, Zheng C, Luo A, Li X, Zhang H, Cheng X, Lu W, Liu P*, Lu B*, Lu Y*. circFBXO7/miR-96-5p/MTSS1 axis is an important regulator in the Wnt signaling pathway in ovarian cancer. Mol Cancer. 2022, 21(1):137. doi: 10.1186/s12943-022-01611-y. PMID: 35768865
Zhou L#, Qiu Q#, Zhou Q#, Li J, Yu M, Li K, Xu L, Ke X, Xu H, Lu B, Wang H, Lu W*, Liu P*, Lu Y*. Long-read sequencing unveils high-resolution HPV integration and its oncogenic progression in cervical cancer. Nat Commun, 2022, 13(1):1-18. doi:10.1038/s41467-022-30190-1. PMID: 35538075
2021年文章
Chen F, Sun C, Yue Z, Zhang Y, Xu W, Shabbir S, Zou L, Lu W, Wang W, Xie Z, Zhou L, Lu Y*, Yu J*. Screening ovarian cancers with Raman spectroscopy of blood plasma coupled with machine learning data processing. Spectrochim Acta A Mol Biomol Spectrosc, 2021, 265:120355. doi: 10.1016/j.saa.2021.120355. PMID: 34530200
Qin J, Zhang S, Poon L, Pan Z, Luo J, Yu N, Wang L, Wu X, Cheng X, Xie X, Lu Y*, Lu W*. Doppler-based predictive model for methotrexate resistance in low-risk gestational trophoblastic neoplasia with myometrial invasion: prospective study of 147 patients. Ultrasound Obstet Gynecol, 2021, 57(5):829-839. doi: 10.1002/uog.22069. PMID: 32385928
Qian X#, Yang J#, Qiu Q#, Li X, Jiang C, Li J, Dong L, Ying K, Lu B, Chen E, Liu P*, Lu Y*. LCAT3, a novel m6A-regulated long non-coding RNA, plays an oncogenic role in lung cancer via binding with FUBP1 to activate c-MYC. J Hematol Oncol, 2021, 14(1):112.
Yue Z, Sun C, Chen F, Zhang Y, Xu W, Shabbir S, Zou L, Lu W, Wang W, Xie Z, Zhou L, Lu Y*, Yu J*. Machine learning-based LIBS spectrum analysis of human blood plasma allows ovarian cancer diagnosis. Biomedical Optics Express, 2021, 12(5):2559-2574, doi： 10.1364/BOE.421961
Qiu Q#, Zhou Q#, Luo A#, Li X, Li K, Li W, Yu M, Amanullah M, Lu B, Lu W*, Liu P*, Lu Y*. Integrated analysis of virus and host transcriptomes in cervical cancer in Asian and Western populations. Genomics, 2021, 113(3):1554-1564. doi: 10.1016/j.ygeno.2021.03.029.
Zhou L#, Wang W#, Wang F#, Yang S, Hu J, Lu B, Pan Z, Ma Y, Zheng M, Zhou L, Lei S, Song P, Liu P*, Lu W*, Lu Y*. Plasma-derived exosomal miR-15a-5p as a promising diagnostic biomarker for early detection of endometrial carcinoma. Mol Cancer, 2021, 20(1):57. doi: 10.1186/s12943-021-01352-4.
Sun X#, Yi J#, Yang J#, Han Y, Qian X, Liu Y, Li J, Lu B, Zhang J, Pan X, Liu Y, Liang M, Chen E*, Liu P*, Lu Y*. An integrated epigenomic–transcriptomic landscape of lung cancer reveals novel methylation driver genes of diagnostic and therapeutic relevance. Theranostics, 2021;11(11): 5346-5364. doi: 10.7150/thno.58385
Pan X#, Geng X#, Liu Y, Yu M, Mishra MK, Xu X, Ding X, Liu P*, Liang M*. Transfer RNA Fragments in the Kidney in Hypertension. Hypertension, 2021, 77(5):1627-1637. doi: 10.1161/HYPERTENSIONAHA.121.16994.
Zhang Y, Liu L, Qiu Q, Ding J*, Lu Y*, Liu P*. Alternative polyadenylation: methods, mechanism, function, and role in cancer. Journal of Experimental & Clinical Cancer Research, 2021, 40(1):51. doi: 10.1186/s13046-021-01852-7.
2020年文章
Sun X#, Yang J#, Yu M#, Yao D, Zhou L, Li X, Qiu Q, Lin W, Lu B, Chen E, Wang P, Chen W, Tao S, Xu H, Williams A, Liu Y, Pan X, Cowley A, Jr, Lu W, Liang M, Liu P*, Lu Y*. Global identification and characterization of tRNA-derived RNA fragment landscapes across human cancers. NAR Cancer, 2020, 2(4): zcaa031.
Yu M, Lu B, Zhang J, Ding J, Liu P, Lu Y*. tRNA-derived RNA fragments in cancer: current status and future perspectives. J Hematol Oncol 13, 121 (2020). https://doi.org/10.1186/s13045-020-00955-6
Liu Y, Han Y, Zhou L, Pan X, Sun X, Liu Y, Liang M, Qin J*, Lu Y*, Liu P*. A comprehensive evaluation of computational tools to identify differential methylation regions using RRBS data. Genomics. 2020;S0888-7543(20)31059-4. doi:10.1016/j.ygeno.2020.07.032
Yao D, Sun X, Zhou L, Amanullah M, Pan X, Liu Y, Liang M, Liu P*, Lu Y*. OncotRF: an online resource for exploration of tRNA-derived fragments in human cancers. RNA Biol. 2020;17(8):1081-1091. doi:10.1080/15476286.2020.1776506.
Han Y#,Liu Y#, Zhou L#, Chen E, Liu P, Pan X*, Lu Y*. Epidemiological Assessment of Imported Coronavirus Disease 2019 (COVID-19) Cases in the Most Affected City Outside of Hubei Province, Wenzhou, China. JAMA Netw Open. 2020;3(4):e206785. Published 2020 Apr 1. doi:10.1001/jamanetworkopen.2020.6785.
Amanullah M#, Yu M#, Sun X#, Luo A, Zhou Q, Zhou L, Hou L, Wang W, Lu W, Liu P*, Lu Y*. MDEHT: a Multivariate Approach for Detecting Differential Expression of MicroRNA Isoform Data in RNA Sequencing Studies Bioinformatics. 2020 May 1;36(9):2657-2664. doi: 10.1093/bioinformatics/btaa015.
Zheng Z, Chen E, Lu W, Mouradian G, Hodges M, Liang M, Liu P*, Lu Y*. Single cell transcriptomic analysis. Compr Physiol. 2020 Mar 12;10(2):767-783. doi: 10.1002/cphy.c190037.
2019年文章
Liu HY#, Zhou L#, Zheng MY#, Huang J, Wan S, Zhu A, Zhang M, Dong A, Hou L, Xu H, Lu B, Lu W, Liu P*, Lu Y*. Diagnostic and clinical utility of whole genome sequencing in a cohort of undiagnosed Chinese families with rare diseases. Sci Rep 9, 19365 (2019) doi:10.1038/s41598-019-55832-1.
Yang J#, Qiu Q#, Qian X, Yi J, Jiao Y, Yu M, Li X, Li J, Mi C, Zhang J, Lu B, Chen E, Liu P*, Lu Y*. Long noncoding RNA LCAT1 functions as a ceRNA to regulate RAC1 function by sponging miR-4715-5p in lung cancer. Mol Cancer. 2019;18(1):171. Published 2019 Nov 29. doi:10.1186/s12943-019-1107-y
Zhang L#, Zhou Q#, Qiu Q#, Hou L, Wu M, Li J, Li X, Lu B, Cheng X, Liu P, Lu W, Lu Y*. CircPLEKHM3 acts as a tumor suppressor through regulation of the miR-9/BRCA1/DNAJB6/KLF4/AKT1 axis in ovarian cancer. Mol Cancer. 2019;18(1):144. Published 2019 Oct 17. doi:10.1186/s12943-019-1080-5
Ilatovskaya DV, Levchenko V, Pavlov TS, Isaeva E, Klemens CA, Johnson J, Liu P, Kriegel AJ, Staruschenko A. Salt-deficient diet exacerbates cystogenesis in ARPKD via epithelial sodium channel (ENaC). EBioMedicine. 2019 Feb;40:663-674. doi: 10.1016/j.ebiom.2019.01.006.
Zheng M#, Hou L#, Ma Y#, Zhou L, Wang F, Cheng B, Wang W, Lu B, Liu P, Lu W, Lu Y*. Exosomal let-7d-3p and miR-30d-5p as diagnostic biomarkers for non-invasive screening of cervical cancer and its precursors. Mol Cancer. 2019;18(1):76. Published 2019 Apr 2. doi:10.1186/s12943-019-0999-x
Han Y#, Yang J#, Qian X, Cheng W, Liu S, Hua X, Zhou L, Yang Y, Wu Q, Liu P*, Lu Y*. DriverML: a machine learning algorithm for identifying driver genes in cancer sequencing studies. Nucleic acids research, doi:10.1093/nar/gkz096 (2019)
Lu B*, Teng X, Fu G, Bao L, Tang J, Sh H, Lu W, Lu Y*. Analysis of PD-L1 expression in trophoblastic tissues and tumors. Human pathology, 2019, 84: 202-212.
Kong Y, Lu Z, Liu P, Liu Y, Wang F, Liang EY, Hou FF, Liang M*. Long Noncoding RNA: Genomics and Relevance to Physiology. Compr Physiol. 2019 Jun 12;9(3):933-946. doi: 10.1002/cphy.c180032. PMID: 31187897
2018年文章
Efanov AA, Brenner AV, Bogdanova TI, Kelly LM, Liu P, Little MP, Wald AI, Hatch M, Zurnadzy LY, Nikiforova MN, Drozdovitch V, Leeman-Neill R, Mabuchi K, Tronko MD, Chanock SJ, Nikiforov YE. Investigation of the Relationship Between Radiation Dose and Gene Mutations and Fusions in Post-Chernobyl Thyroid Cancer. J Natl Cancer Inst. 2018 Apr 1;110(4):371-378. doi: 10.1093/jnci/djx209.
Sun X#, Han Y#, Zhou L, Chen E, Lu B, Liu Y, Pan X, Cowley AW Jr, Liang M, Wu Q, Lu Y*, Liu P*. A comprehensive evaluation of alignment software for reduced representation bisulfite sequencing data. Bioinformatics. 2018 Aug 15;34(16):2715-2723. doi: 10.1093/bioinformatics/bty174.
Yao D, Zhang L, Zheng M, Sun X, Lu Y*, Liu P*. Circ2Disease: a manually curated database of experimentally validated circRNAs in human disease. Sci Rep. 2018 Jul 20;8(1):11018. doi: 10.1038/s41598-018-29360-3.
Li X, Li J, Wu P, Zhou L, Lu B, Ying K, Chen E*, Lu Y*, Liu P*. Smoker and non-smoker lung adenocarcinoma is characterized by distinct tumor immune microenvironments. OncoImmunology. 2018 Jul 30;7(10):e1494677. doi: 10.1080/2162402X.2018.1494677
Williams AM, Liu Y, Regner KR, Jotterand F, Liu P, Liang M. Artificial intelligence, physiological genomics, and precision medicine. Physiol Genomics. 2018 Apr 1;50(4):237-243. doi: 10.1152/physiolgenomics.00119.2017.
Widlansky ME, Jensen DM, Wang J, Liu Y, Geurts AM, Kriegel AJ, Liu P, Ying R, Zhang G, Casati M, Chu C, Malik M, Branum A, Tanner MJ, Tyagi S, Usa K, Liang M. miR-29 contributes to normal endothelial function and can restore it in cardiometabolic disorders. EMBO Mol Med. 2018 Mar;10(3). pii: e8046. doi: 10.15252/emmm.201708046.
Stodola TJ, Liu P, Liu Y, Vallejos AK, Geurts AM, Greene AS, Liang M. Genome-wide map of proximity linkage to renin proximal promoter in rat. Physiol Genomics. 2018 May 1;50(5):323-331. doi: 10.1152/physiolgenomics.00132.2017.
Cheng Y, Song H, Pan X, Xue H, Wan Y, Wang T, Tian Z, Hou E, Lanza IR, Liu P, Liu Y, Laud PW, Usa K, He Y, Liang M. Urinary Metabolites Associated with Blood Pressure on a Low- or High-Sodium Diet. Theranostics. 2018 Feb 5;8(6):1468-1480. doi: 10.7150/thno.22018.
Evans LC, Dayton A, Yang C, Liu P, Kurth T, Ahn KW, Komas S, Stingo FC, Laud PW, Vannucci M, Liang M, Cowley AW Jr. Transcriptomic analysis reveals inflammatory and metabolic pathways that are regulated by renal perfusion pressure in the outer medulla of Dahl-S rats. Physiol Genomics. 2018 Jun 1;50(6):440-447. doi: 10.1152/physiolgenomics.00034.2018.
Li Y, Pan X, Roberts ML, Liu P, Kotchen TA, Cowley AW Jr, Mattson DL, Liu Y, Liang M, Kidambi S. Stability of global methylation profiles of whole blood and extracted DNA under different storage durations and conditions. Epigenomics. 2018 Jun;10(6):797-811. doi: 10.2217/epi-2018-0025.
Liu Y, Usa K, Wang F, Liu P, Geurts AM, Li J, Williams AM, Regner KR, Kong Y, Liu H, Nie J, Liang M. MicroRNA-214-3p in the Kidney Contributes to the Development of Hypertension. J Am Soc Nephrol. 2018 Oct;29(10):2518-2528. doi: 10.1681/ASN.2018020117.
Wei Q, Sun H, Song S, Liu Y, Liu P, Livingston MJ, Wang J, Liang M, Mi QS, Huo Y, Nahman NS, Mei C, Dong Z. microRNA-668 represses MTP18 to preserve mitochondrial dynamics in ischemic acute kidney injury. J Clin Invest. 2018 Dec 3;128(12):5448-5464. doi: 10.1172/JCI121859.
Liu P, Liu Y, Liu H, Pan X, Li Y, Usa K, M Mishra, Nie J, Liang M*. Role of DNA De Novo (De)Methylation in the Kidney in Salt-Induced Hypertension. Hypertension. 2018;72:1160–1171. doi: 10.1161/HYPERTENSIONAHA.118.11650
Liu Y#, Liu P#, Wen W, James MA, Wang Y, Bailey-Wilson JE, et al. Haplotype and cell proliferation analyses of candidate lung cancer susceptibility genes on chromosome 15q24-25.1. Cancer Res. 2009;69:7844-50.
2017年文章
Panebianco F, Kelly LM, Liu P, Zhong S, Dacic S, Wang X, Singhi AD, Dhir R, Chiosea SI, Kuan SF, Bhargava R, Dabbs D, Trivedi S, Gandhi M, Diaz R, Wald AI, Carty SE, Ferris RL, Lee AV, Nikiforova MN, Nikiforov YE. THADA fusion is a mechanism of IGF2BP3 activation and IGF1R signaling in thyroid cancer. Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):2307-2312. doi: 10.1073/pnas.1614265114.
Liu P, Iden M, Fye S, Huang YW, Hopp E, Chu C, Lu Y, Rader JS. Targeted, deep sequencing reveals full methylation profiles of multiple HPV types and potential biomarkers for cervical cancer progression. Cancer Epidemiol Biomarkers Prev. 2017 Apr;26(4):642-650.
Zhang H, Lu Y, Chen E, Li X, Lv B, Vikis HG, Liu P*. XRN2 promotes EMT and metastasis through regulating maturation of miR-10a. Oncogene. 2017 Jul 6;36(27):3925-3933.
Xu J, Zhou W, Yang F, Chen G, Li H, Zhao Y, Liu P, Li H, Tan M, Xiong X, Sun Y. The β-TrCP-FBXW2-SKP2 axis regulates lung cancer cell growth with FBXW2 acting as a tumour suppressor. Nat Commun. 2017;8:14002.
Yu Y, Lu B, Lu W, Li S, Li X, Wang X, Wan X, Chen Y, Feng S, Jia Y, Yang R, Tang F, Li X, Zhang S, Wang X, Wei H, Peng Z, Lu L, Zhong H, Zhao L, Huang Z, Lin L, Shen W, Lu Y, Cao Z, Zou J, Ma Y, Chen X, Tian Q, Lu S, Liu P*, Ma D*, Xie X*, Cheng X*. Whole-exome sequencing reveals genetic variants in ERC1 and KCNG4 associated with complete hydatidiform mole in Chinese Han women. Oncotarget. 2017 Sep 8;8(43):75264-75271. doi: 10.18632/oncotarget.20769. eCollection
Chuppa S, Liang M, Liu P, Liu Y, Casati MC, Cowley AW, Patullo L, Kriegel AJ. MicroRNA-21 regulates peroxisome proliferator-activated receptor alpha, a molecular mechanism of cardiac pathology in Cardiorenal Syndrome Type 4. Kidney Int. 2018 Feb;93(2):375-389. doi: 10.1016/j.kint.2017.05.014.
Baker MA, Davis SJ, Liu P, Pan X, Williams AM, Iczkowski KA, Gallagher ST, Bishop K, Regner KR, Liu Y, Liang M Tissue-Specific MicroRNA Expression Patterns in Four Types of Kidney Disease. J Am Soc Nephrol. 2017 Oct;28(10):2985-2992.
Gao F, Liu P, Narayanan J, Yang M, Fish BL, Liu Y, Liang M, Jacobs ER, Medhora M. Changes in miRNA in the lung and whole blood after whole thorax irradiation in rats. Sci Rep. 2017 Mar 17;7:44132. doi: 10.1038/srep44132.
2016年文章
Xu H, Ma Y, Zhang Y, Pan Z, Lu Y, Liu P, Lu B. Identification of Cathepsin K in the Peritoneal Metastasis of Ovarian Carcinoma Using In-silico, Gene Expression Analysis. J Cancer. 2016;7(6):722-9.
Wei Q, Liu Y, Liu P, Hao J, Liang M, Mi QS, Chen JK, Dong Z. MicroRNA-489 Induction by Hypoxia-Inducible Factor-1 Protects against Ischemic Kidney Injury. J Am Soc Nephrol. 2016;27(9):2784-96.
Cowley AW Jr, Yang C, Kumar V, Lazar J, Jacob H, Geurts AM, Liu P, Dayton A, Kurth T, Liang M. Pappa2 is linked to salt-sensitive hypertension in Dahl S rats. Physiol Genomics. 2016;48(1):62-72.
2015年文章
Chu C, Fang Z, Hua X, Yang Y, Chen E, Cowley AW Jr, Liang M, Liu P*, Lu Y*. deGPS is a powerful tool for detecting differential expression in RNA-sequencing studies. BMC Genomics. 2015;16(1):455.
Geurts AM, Mattson DL, Liu P, Cabacungan E, Skelton MM, Kurth TM, Yang C, Endres BT, Klotz J, Liang M, Cowley AW Jr. Maternal diet during gestation and lactation modifies the severity of salt-induced hypertension and renal injury in dahl salt-sensitive rats. Hypertension. 2015 Feb;65(2):447-55. doi: 10.1161/HYPERTENSIONAHA.114.04179. Epub 2014 Dec 1.
Du M, Yuan T, Schilter KF, Dittmar RL, Mackinnon A, Huang X, Tschannen M, Worthey E, Jacob H, Xia S, Gao J, Tillmans L, Lu Y, Liu P, Thibodeau SN, Wang L. Prostate cancer risk locus at 8q24 as a regulatory hub by physical interactions with multiple genomic loci across the genome. Hum Mol Genet. 2015 Jan 1;24(1):154-66.
Huang X, Yuan T, Liang M, Du M, Xia S, Dittmar R, Wang D, See W, Costello BA, Quevedo F, Tan W, Nandy D, Bevan GH, Longenbach S, Sun Z, Lu Y, Wang T, Thibodeau SN, Boardman L, Kohli M, Wang L. Exosomal miR-1290 and miR-375 as prognostic markers in castration-resistant prostate cancer. Eur Urol. 2015 Jan;67(1):33-41.
2014年文章
Wilson IM, Vucic EA, Enfield KS, Thu KL, Zhang YA, Chari R, Lockwood WW, Radulovich N, Starczynowski DT, Banáth JP, Zhang M, Pusic A, Fuller M, Lonergan KM, Rowbotham D, Yee J, English JC, Buys TP, Selamat SA, Laird-Offringa IA, Liu P, Anderson M, You M, Tsao MS, Brown CJ, Bennewith KL, Macaulay CE, Karsan A, Gazdar AF, Lam S, Lam WL. EYA4 is inactivated biallelically at a high frequency in sporadic lung cancer and is associated with familial lung cancer risk. Oncogene. 2014 Sep 4;33(36):4464-73.
Leeman-Neill RJ, Kelly LM, Liu P, Brenner AV, Little MP, Bogdanova TI, Evdokimova VN, Hatch M, Zurnadzy LY, Nikiforova MN, Yue NJ, Zhang M, Mabuchi K, Tronko MD, Nikiforov YE. ETV6-NTRK3 is a common chromosomal rearrangement in radiation-associated thyroid cancer. Cancer. 2014 Mar 15;120(6):799-807.
Liu Y*, Liu P*, Yang C, Cowley AW, Liang M. Base-Resolution Maps of 5-Methylcytosine and 5-Hydroxymethylcytosine in Dahl S Rats: Effect of Salt and Genomic Sequence. Hypertension. 2014;63(4):827-38 (co-first author).
Morrison CD*, Liu P*, Woloszynska-Read A, Zhang J, Luo W, Qin M, Bshara W, Conroy JM, Sabatini L, Vedell P, Xiong D, Liu S, Wang J, Shen H, Li Y, Omilian AR, Hill A, Head K, Guru K, Kunnev D, Leach R, Eng KH, Darlak C, Hoeflich C, Veeranki S, Glenn S, You M, Pruitt SC, Johnson CS, Trump DL. Whole Genome Sequencing Identifies Genomic Heterogeneity at a Nucleotide and Chromosomal Level in Bladder Cancer. Proc Natl Acad Sci U S A. 2014;111(6):E672-81. (co-first author).
Kelly LM*, Barila G*, Liu P*, Evdokimova VN, Trivedi S, Panebianco F, Gandhi M, Carty SE, Hodak SP, Luo J, Dacic S, Yu YP, Nikiforova MN, Ferris RL, Altschuler DL, Nikiforov YE. Identification of the transforming STRN-ALK fusion as a potential therapeutic target in the aggressive forms of thyroid cancer. Proc Natl Acad Sci U S A. 2014;111(11):4233-8 (co-first author).
Cowley AW Jr, Moreno C, Jacob HJ, Peterson CB, Stingo FC, Ahn KW, Liu P, Vannucci M, Laud PW, Reddy P, Lazar J, Evans L, Yang C, Kurth T, Liang M. Characterization of biological pathways associated with a 1.37 Mbp genomic region protective of hypertension in Dahl S rats. Physiol Genomics. 2014 Jun 1;46(11):398-410.
Wang LS, Burke C, Hasson H, Kuo CT, Molmenti C, Seguin C, Liu P, Huang TH, Frankel WL, Stoner G. A Phase 1b Study of the Effects of Black Raspberries on Rectal Polyps in Patients with Familial Adenomatous Polyposis. Cancer Prev Res (Phila). 2014 Jul;7(7):666-74.
Puissant MM, Echert AE, Yang C, Mouradian GC Jr, Novotny T, Liu P, Liang M, Hodges MR. RNASeq-derived transcriptome comparisons reveal neuromodulatory deficiency in the CO2 - insensitive Brown Norway rat. J Physiol. 2014 Nov 10. [Epub ahead of print]
Wang F, Li L, Xu H, Liu Y, Yang C, Cowley AW Jr, Wang N*, Liu P*, Liang M*. Characteristics of long non-coding RNAs in the Brown Norway rat and alterations in the Dahl salt-sensitive rat. Sci Rep. 2014 Nov 21;4:7146. doi: 10.1038/srep07146 (co-corresponding author).
Nicastro HL, Grubbs CJ, Margaret Juliana M, Bode AM, Kim MS, Lu Y, You M, Milne GL, Boring D, Steele VE, Lubet RA. Preventive effects of NSAIDs, NO-NSAIDs, and NSAIDs plus difluoromethylornithine in a chemically induced urinary bladder cancer model. Cancer Prev Res (Phila). 2014 Feb;7(2):246-54.
Chen E, Liu P, Lu Y. Cancer genomics: new software tools making sequencing more accessible. Pers. Med. (2014) 11(2), 127–130.
Li L, Chen E, Yang C, Zhu J, Jayaraman P, De Pons J, Kaczorowski CC, Jacob HJ, Greene AS, Hodges MR, Cowley AW Jr, Liang M, Xu H, Liu P*, Lu Y*. Improved rat genome gene prediction by integration of ESTs with RNA-Seq information. Bioinformatics. 2015 Jan 1;31(1):25-32. doi: 10.1093/bioinformatics/btu608. (co-corresponding author).
2013年文章
Leikauf GD, Concel VJ, Bein K, Liu P, Berndt A, Martin TM, Ganguly K, Jang AS, Brant KA, Dopico RA Jr, Upadhyay S, Cario C, Di YP, Vuga LJ, Kostem E, Eskin E, You M, Kaminski N, Prows DR, Knoell DL, Fabisiak JP. Functional genomic assessment of phosgene-induced acute lung injury in mice. Am J Respir Cell Mol Biol. 2013 Sep;49(3):368-8
Yang C, Stingo FC, Ahn KW, Liu P, Vannucci M, Laud PW, Skelton M, O'Connor P, Kurth T, Ryan RP, Moreno C, Tsaih SW, Patone G, Hummel O, Jacob HJ, Liang M, Cowley AW Jr. Increased proliferative cells in the medullary thick ascending limb of the loop of Henle in the Dahl salt-sensitive rat. Hypertension. 2013 Jan;61(1):208-15.
Kaczorowski CC, Stodola TJ, Hoffmann BR, Prisco AR, Liu PY, Didier DN, Karcher JR, Liang M, Jacob HJ, Greene AS. Targeting the endothelial progenitor cell surface proteome to identify novel mechanisms that mediate angiogenic efficacy in a rodent model of vascular disease. Physiol Genomics. Physiol Genomics. 2013 Nov 1;45(21):999-1011.
Kriegel AJ*, Liu Y*, Liu P*, Baker MA, Hodges MR, Hua X, Liang M. Characteristics of MicroRNAs Enriched in Specific Cell Types and Primary Tissue Types in Solid Organs. Physiol Genomics. 2013 Dec 2;45(23):1144-56. (co-first author).
Vedell P, Lu Y, Grubbs C, Yin Y, Jiang H, Bland K, Muccio DD, Cvetkovic D, You M, Lubet R. Effects on Gene Expression in Rat Liver after Administration of RXR Agonists:UAB30, 4-Methyl-UAB30, and Targretin (Bexarotene). Mol Pharmacol 2013;83(3):698-708
Hua X, Xu H, Yang Y, Zhu J, Liu P, Lu Y*. DrGaP: A Powerful Tool for Identifying Driver Genes and Pathways in Cancer Sequencing Studies. Am J Hum Genet. 2013;93(3):439-51 (co-corresponding author).
Lu Y, You M, Ghazoui Z, Liu P, Vedell PT, Wen W, Bode AM, Grubbs CJ, Lubet RA. Concordant Effects of Aromatase Inhibitors on Gene Expression in ER+ Rat and Human Mammary Cancers and Modulation of the Proteins Coded by these Genes. Cancer Prev Res (Phila). 2013 Nov;6(11):1151-61.
2012年文章
Liu P, Liu H, Lu Y, Wen W, Jia D, Wang Y, You M. Genome-wide association and fine mapping of genetic loci predisposing to colon carcinogenesis in mice. Mol Can Res 2012;10(1):66-74.
Leikauf GD, Pope-Varsalona H, Concel VJ, Liu P, Bein K, Berndt A, Martin TM, Ganguly K, Jang AS, Brant KA, Dopico RA Jr, Upadhyay S, Di YP, Li Q, Hu Z, Vuga LJ, Medvedovic M, Kaminski N, You M, Alexander DC, McDunn JE, Prows DR, Knoell DL, Fabisiak JP. Integrative Assessment of Chlorine-induced Acute Lung Injury in Mice. Am J Respir Cell Mol Biol. 2012 47(2):234-44.
Li HH, Li Q, Liu P, Liu Y, Li J, Wasserloos K, Chao W, You M, Oury TD, Chhinder S, Hackam DJ, Billiar TR, Leikauf GD, Pitt BR, Zhang LM. WNT1 Inducible Signaling Pathway Protein 1 (WISP1) Contributes to Ventilator-Induced Lung Injury. Am J Respir Cell Mol Biol. 2012 47(4):528-35.
Xiong D, Li G, Li K, Xu Q, Pan Z, Ding F, Vedell P, Liu P, Cui P, Hua X, Jiang H, Yin Y, Zhu Z, Li X, Zhang B, Ma D, Wang Y, You M. Exome sequencing identifies MXRA5 as a novel cancer gene frequently mutated in non-small cell lung carcinoma from Chinese patients. Carcinogenesis. 2012 33(9):1797-805
Lu Y, Liu P, Van den Bergh F, Zellmer V, James M, Wen W, Grubbs CJ, Lubet RA, and You M. Modulation of Gene Expression and Cell Cycle Signaling Pathways in Iressa-treated Urinary Bladder Cancer in Rats. Cancer Prevention Research. 2012 Feb;5(2):248-59.
Liu P, Lu Y, Liu H, Wen W, Jia D, Wang Y, You M. Genome-wide association and fine mapping of genetic loci predisposing to colon carcinogenesis in mice. Mol Cancer Res. 2012 Jan; 10(1):66-74. Epub 2011 Nov 29.
Lu Y, Govindan R, Wang L, Liu P, Goodgame B, Wen W, Sezhiyan A, Li Y, Hua X, Wang Y, Yang P, You M. MicroRNA profiling and prediction of recurrence/relapse-free survival in stage I lung cancer. Carcinogenesis. 2012 May;33(5):1046-54.
Lu Y, Wang L, Liu P, Yang P, You M. Gene-expression signature predicts postoperative recurrence in stage I non-small cell lung cancer patients. PLoS One. 2012;7(1):e30880..
Liu P, Morrison C, Wang L, Xiong D, Vedell P, Cui P, Hua X, Ding F, Lu Y, et al. Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing. Carcinogenesis. 2012;33(7):1270-6
2011年文章
Zhang Q, Pan J, Zhang J, Liu P, Chen R, Chen DR, Lubet RA, Wang Y, You M. Aerosolized bexarotene inhibits lung tumorigenesis without increasing plasma triglyceride and cholesterol level in mice. Cancer Prev Res (Phila). 2011 Feb;4(2):270-6
Leikauf GD, Concel VJ, Liu P, Bein K, Berndt A, Ganguly K, Jang AS, Brant KA, Dietsch M, Pope-Varsalona H, Dopico RA Jr, Di YP, Li Q, Vuga LJ, Medvedovic M, Kaminski N, You M, Prows DR. Haplotype association mapping of acute lung injury in mice implicates activin a receptor, type 1. Am J Respir Crit Care Med. 2011;183(11):1499-509.
Freedman ML, Monteiro AN, Gayther SA, Coetzee GA, Risch A, Plass C, Casey G, De Biasi M, Carlson C, Duggan D, James M, Liu P, Tichelaar JW, Vikis HG, You M, Mills IG. Principles for the post-GWAS functional characterization of cancer risk loci. Nat Genet. 2011;43(6):513-8
Lu Y, Liu P, Wen W, Grubbs CJ, Townsend RR, Malone JP, et al. Cross-species comparison of orthologous gene expression in human bladder cancer and carcinogen-induced rodent models. Am J Translational Res. 2011;3:8-21.
Fu H, Zhang J, Pan J, Zhang Q, Lu Y, Wen W, Lubet RA, Szabo E, Chen R, Wang Y, Chen DR, You M. Chemoprevention of Lung Carcinogenesis by the Combination of Aerosolized Budesonide and Oral Pioglitazone in A/J Mice. Mol Carcinog. 2011 Mar 3. doi: 10.1002/mc.20751.
Lubet RA, Lu Y, Bode AM, You M, Verney ZM, Steele VE, Townsend R, Juliana MM, Grubbs CJ. Efficacy of the EGFr inhibitor Iressa on development of chemically-induced urinary bladder cancers: dose dependency and modulation of biomarkers. Oncol Rep. 2011 25(5):1389-97.
Lu Y, Liu YZ, Liu PY, Dvornyk V, Deng HW. A bootstrap-based regression method for comprehensive discovery of differential gene expressions: An application to the osteoporosis study. Eur J Med Genet. 2011 Jul 30.
Vikis HG, Gelman AE, Franklin A, Stein L, Rymaszewski A, Zhu J, Liu P, Tichelaar JW, Krupnick AS, You M. Neutrophils are required for 3-methylcholanthrene-initiated, butylated hydroxytoluene-promoted lung carcinogenesis. Mol Carcinog. 2011. doi: 10.1002/mc.20870
2010年文章
Leikauf GD, Pope-Varsalona H, Concel VJ, Liu P, Bein K, Brant KA, et al. Functional genomics of chlorine-induced acute lung injury in mice. Proc Am Thorac Soc. 2010;7:294-6.
Liu P, Lu Y, Recker RR, Deng HW, Dvornyk V. ALOX12 gene is associated with the onset of natural menopause in white women. Menopause. 2010;17:152-6.
Liu P, Lu Y, Recker RR, Deng HW, Dvornyk V. Association analyses suggest multiple interaction effects of the methylenetetrahydrofolate reductase polymorphisms on timing of menarche and natural menopause in white women. Menopause. 2010;17:185-90.
Liu P, Vikis HG, Lu Y, Wang Y, Schwartz AG, Pinney SM, et al. Cumulative effect of multiple loci on genetic susceptibility to familial lung cancer. Cancer Epidemiol Biomarkers Prev. 2010;19:517-24.
Liu P#, Yang P#, Wu X#, Vikis HG, Lu Y, Wang Y, et al. A second genetic variant on chromosome 15q24-25.1 associates with lung cancer. Cancer Res. 2010;70:3128-35.
Lu Y, Liu P, James M, Vikis HG, Liu H, Wen W, et al. Genetic variants cis-regulating Xrn2 expression contribute to the risk of spontaneous lung tumor. Oncogene. 2010;29:1041-9.
Lu Y, Liu P, Recker RR, Deng HW, Dvornyk V. TNFRSF11A and TNFSF11 are associated with age at menarche and natural menopause in white women. Menopause. 2010;17:1048-54.
Wang Y, James M, Wen W, Lu Y, Szabo E, Lubet RA, et al. Chemopreventive effects of pioglitazone on chemically induced lung carcinogenesis in mice. Mol Cancer Ther. 2010;9:3074-82.
2010年以前文章
Chen Y, Shen H, Yang F, Liu PY, Tang N, Recker RR, et al. Choice of study phenotype in osteoporosis genetic research. J Bone Miner Metab. 2009;27:121-6.
Liu Y#, Liu P#, Wen W, James MA, Wang Y, Bailey-Wilson JE, et al. Haplotype and cell proliferation analyses of candidate lung cancer susceptibility genes on chromosome 15q24-25.1. Cancer Res. 2009;69:7844-50.
Wang JC, Cruchaga C, Saccone NL, Bertelsen S, Liu P, Budde JP, et al. Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5. Hum Mol Genet. 2009;18:3125-35.
James MA, Lu Y, Liu Y, Vikis HG, You M. RGS17, an overexpressed gene in human lung and prostate cancer, induces tumor cell proliferation through the cyclic AMP-PKA-CREB pathway. Cancer Res. 2009;69:2108-16.
Liu P, Vikis H, James M, Lu Y, Wang DL, Liu HB, et al. Identification of Las2, a major modifier gene affecting the Pas1 mouse lung tumor susceptibility locus. Cancer Res. 2009;69:6290-8.
You M#*, Wang D#, Liu P#, Vikis H#, James M,Lu Y, et al. Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene. Clin Cancer Res. 2009;15:2666-74.
Tan LJ, Liu YZ, Xiao P, Yang F, Tang ZH, Liu PY, et al. Evidence for major pleiotropic effects on bone size variation from a principal component analysis of 451 Caucasian families. Acta Pharmacol Sin. 2008;29:745-51.
Liu P, Vikis HG, Wang D, Lu Y, Wang Y, Schwartz AG, et al. Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer. J Natl Cancer Inst. 2008;100:1326-30.
Deng FY, Xiao P, Lei SF, Zhang L, Yang F, Tang ZH, et al. Bivariate whole genome linkage analysis for femoral neck geometric parameters and total body lean mass. J Bone Miner Res. 2007;22:808-16.
Zhao LJ, Liu YJ, Liu PY, Hamilton J, Recker RR, Deng HW. Relationship of obesity with osteoporosis. J Clin Endocrinol Metab. 2007;92:1640-6.
Liu P, Vikis H, Lu Y, Wang D, You M. Large-scale in silico mapping of complex quantitative traits in inbred mice. PLoS One. 2007;2:e651.
Lu Y, Yi Y, Liu P, Wen W, James M, Wang D, et al. Common human cancer genes discovered by integrated gene-expression analysis. PLoS One. 2007;2:e1149.
Dvornyk V, Long JR, Liu PY, Shen H, Recker RR, Deng HW. Polymorphisms of the vitamin D receptor gene predict the onset of surgical menopause in Caucasian females. Gynecol Endocrinol. 2006;22:552-6.
Dvornyk V, Long JR, Liu PY, Zhao LJ, Shen H, Recker RR, et al. Predictive factors for age at menopause in Caucasian females. Maturitas. 2006;54:19-26.
Liu P, Wang Y, Vikis H, Maciag A, Wang D, Lu Y, et al. Candidate lung tumor susceptibility genes identified through whole-genome association analyses in inbred mice. Nat Genet. 2006;38:888-95.
Lou XY, Ma JZ, Yang MC, Zhu J, Liu PY, Deng HW, et al. Improvement of mapping accuracy by unifying linkage and association analysis. Genetics. 2006;172:647-61.
Xiao P#, Liu P#, Weber JL, Papasian CJ, Recker RR, Deng HW. Paternal uniparental isodisomy of the entire chromosome 3 revealed in a person with no apparent phenotypic disorders. Hum Mutat. 2006;27:133-7. (co-first author)
Zhao LJ, Liu PY, Recker R, Deng HW. Correlation of transmenopausal bone mass in healthy white women: a long-term longitudinal study. Osteoporos Int. 2006;17:1501-5.
Liu P, Lu Y, Deng HW. Accurate haplotype inference for multiple linked single-nucleotide polymorphisms using sibship data. Genetics. 2006;174:499-509.
Liu P, Zhu J, Lu Y. Impacts of QTL x environment interactions on genetic response to marker-assisted selection. Yi Chuan Xue Bao. 2006;33:63-71.
Lu Y, Lemon W, Liu PY, Yi Y, Morrison C, Yang P, et al. A gene expression signature predicts survival of patients with stage I non-small cell lung cancer. PLoS Med. 2006;3:e467.
Lu Y, Yao R, Yan Y, Wang Y, Hara Y, Lubet RA, et al. A gene expression signature that can predict green tea exposure and chemopreventive efficacy of lung cancer in mice. Cancer Res. 2006;66:1956-63.
Yan Y, Lu Y, Wang M, Vikis H, Yao R, Wang Y, et al. Effect of an epidermal growth factor receptor inhibitor in mouse models of lung cancer. Mol Cancer Res. 2006;4:971-81.
Yao R, Wang Y, Lu Y, Lemon WJ, End DW, Grubbs CJ, et al. Efficacy of the farnesyltransferase inhibitor R115777 in a rat mammary tumor model: role of Ha-ras mutations and use of microarray analysis in identifying potential targets. Carcinogenesis. 2006;27:1420-31.
Zhang YY, Liu PY, Lu Y, Xiao P, Liu YJ, Long JR, et al. Tests of linkage and association of PTH/PTHrP receptor type 1 gene with bone mineral density and height in Caucasians. J Bone Miner Metab. 2006;24:36-41.
Dvornyk V, Liu PY, Long JR, Zhang YY, Lei SF, Recker RR, et al. Contribution of genotype and ethnicity to bone mineral density variation in Caucasians and Chinese: a test for five candidate genes for bone mass. Chin Med J (Engl). 2005;118:1235-44.
Long JR, Xu H, Zhao LJ, Liu PY, Shen H, Liu YJ, et al. The oestrogen receptor alpha gene is linked and/or associated with age of menarche in different ethnic groups. J Med Genet. 2005;42:796-800.
Shen H, Liu Y, Liu P, Recker RR, Deng HW. Nonreplication in genetic studies of complex diseases--lessons learned from studies of osteoporosis and tentative remedies. J Bone Miner Res. 2005;20:365-76.
Shen H, Long JR, Xiong DH, Liu YJ, Liu YZ, Xiao P, et al. Mapping quantitative trait loci for cross-sectional geometry at the femoral neck. J Bone Miner Res. 2005;20:1973-82.
Xiong DH, Liu YZ, Liu PY, Zhao LJ, Deng HW. Association analysis of estrogen receptor alpha gene polymorphisms with cross-sectional geometry of the femoral neck in Caucasian nuclear families. Osteoporos Int. 2005;16:2113-22.
Xiong DH, Xu FH, Liu PY, Shen H, Long JR, Elze L, et al. Vitamin D receptor gene polymorphisms are linked to and associated with adult height. J Med Genet. 2005;42:228-34.
Liu PY, Zhang YY, Lu Y, Long JR, Shen H, Zhao LJ, et al. A survey of haplotype variants at several disease candidate genes: the importance of rare variants for complex diseases. J Med Genet. 2005;42:221-7.
Liu YJ, Liu PY, Long J, Lu Y, Elze L, Recker RR, et al. Linkage and association analyses of the UCP3 gene with obesity phenotypes in Caucasian families. Physiol Genomics. 2005;22:197-203.
Liu YZ, Dvornyk V, Lu Y, Shen H, Lappe JM, Recker RR, et al. A novel pathophysiological mechanism for osteoporosis suggested by an in vivo gene expression study of circulating monocytes. J Biol Chem. 2005;280:29011-6.
Long JR, Liu PY, Lu Y, Dvornyk V, Xiong DH, Zhao LJ, et al. Tests of linkage and/or association of TGF-beta1 and COL1A1 genes with bone mass. Osteoporos Int. 2005;16:86-92.
Lu Y, Zhu J, Liu PY. A two-step strategy for detecting differential gene expression of cDNA microarray data. Curr Genet. 2005;47:121-131.
Lu Y, Liu PY, Xiao P, Deng HW. Hotelling's T2 multivariate profiling for detecting differential expression in microarrays. Bioinformatics. 2005;21:3105-13.
Xiao P, Liu PY, Lu Y, Guo YF, Xiong DH, Li LH, et al. Association tests of interleukin-6 (IL-6) and type II tumor necrosis factor receptor (TNFR2) genes with bone mineral density in Caucasians using a re-sampling approach. Hum Genet. 2005;117:340-8.
Zhang YY, Liu PY, Lu Y, Davies KM, Dvornyk V, Recker RR, et al. Race and sex differences and contribution of height: a study on bone size in healthy Caucasians and Chinese. Am J Hum Biol. 2005;17:568-75.
Dvornyk V, Long JR, Xiong DH, Liu PY, Zhao LJ, Shen H, et al. Current limitations of SNP data from the public domain for studies of complex disorders: a test for ten candidate genes for obesity and osteoporosis. BMC Genet. 2004;5:4.
Li MX, Liu PY, Li YM, Qin YJ, Liu YZ, Deng HW. A major gene model of adult height is suggested in Chinese. J Hum Genet. 2004;49:148-53.
Liu PY, Li YM, Li MX, Malkin I, Qin YJ, Chen XD, et al. Lack of evidence for a major gene in the Mendelian transmission of BMI in Chinese. Obes Res. 2004;12:1967-73.
Liu PY, Qin YJ, Recker RR, Deng HW. Evidence for a major gene underlying bone size variation in the Chinese. Am J Hum Biol. 2004;16:68-77.
Liu PY, Qin YJ, Zhou Q, Recker RR, Deng HW. Complex segregation analyses of bone mineral density in Chinese. Ann Hum Genet. 2004;68:154-64.
Long JR, Zhang YY, Liu PY, Liu YJ, Shen H, Dvornyk V, et al. Association of estrogen receptor alpha and vitamin D receptor gene polymorphisms with bone mineral density in Chinese males. Calcif Tissue Int. 2004;74:270-6.
Shen H, Zhang YY, Long JR, Xu FH, Liu YZ, Xiao P, et al. A genome-wide linkage scan for bone mineral density in an extended sample: evidence for linkage on 11q23 and Xq27. J Med Genet. 2004;41:743-51.
Liu P, Zhu J, Lu Y. Marker-assisted selection in segregating generations of self-fertilizing crops. Theor Appl Genet. 2004;109:370-6.
Liu PY, Lu Y, Long JR, Xu FH, Shen H, Recker RR, et al. Common variants at the PCOL2 and Sp1 binding sites of the COL1A1 gene and their interactive effect influence bone mineral density in Caucasians. J Med Genet. 2004;41:752-7.
Liu YJ, Rocha-Sanchez SM, Liu PY, Long JR, Lu Y, Elze L, et al. Tests of linkage and/or association of the LEPR gene polymorphisms with obesity phenotypes in Caucasian nuclear families. Physiol Genomics. 2004;17:101-6.
Long JR, Liu PY, Liu YJ, Lu Y, Shen H, Zhao LJ, et al. APOE haplotypes influence bone mineral density in Caucasian males but not females. Calcif Tissue Int. 2004;75:299-304.
Long JR, Liu PY, Lu Y, Xiong DH, Zhao LJ, Zhang YY, et al. Association between COL1A1 gene polymorphisms and bone size in Caucasians. Eur J Hum Genet. 2004;12:383-8.
Long JR, Zhao LJ, Liu PY, Lu Y, Dvornyk V, Shen H, et al. Patterns of linkage disequilibrium and haplotype distribution in disease candidate genes. BMC Genet. 2004;5:11.
Lu Y, Liu PY, Liu YJ, Xu FH, Deng HW. Quantifying the relationship between gene expressions and trait values in general pedigrees. Genetics. 2004;168:2395-405.
Zhao LJ, Liu PY, Long JR, Lu Y, Xu FH, Zhang YY, et al. Test of linkage and/or association between the estrogen receptor alpha gene with bone mineral density in Caucasian nuclear families. Bone. 2004;35:395-402.
Deng HW, Li YM, Li MX, Liu PY. Robust indices of Hardy-Weinberg disequilibrium for QTL fine mapping. Hum Hered. 2003;56:160-5.
Long J, Liu P, Zhang Y, Shen H, Liu Y, Dvornyk V, et al. Interaction effects between estrogen receptor alpha gene, vitamin D receptor gene, age, and sex on bone mineral density in Chinese. J Hum Genet. 2003;48:514-9.
Zhang YY, Liu PY, Deng HW. The impact of reproductive and menstrual history on bone mineral density in Chinese women. J Clin Densitom. 2003;6:289-96.
Zhang YY, Long JR, Liu PY, Liu YJ, Shen H, Zhao LJ, et al. Estrogen receptor alpha and vitamin D receptor gene polymorphisms and bone mineral density: association study of healthy pre- and postmenopausal Chinese women. Biochem Biophys Res Commun. 2003;308:777-83.
Liu P, Zhu J, Lou X, Lu Y. A method for marker-assisted selection based on QTLs with epistatic effects. Genetica. 2003;119:75-86.
Long JR, Liu PY, Liu YJ, Lu Y, Xiong DH, Elze L, et al. APOE and TGF-beta1 genes are associated with obesity phenotypes. J Med Genet. 2003;40:918-24.
